Famous Fantastic Mysteries was an American science fiction and fantasy pulp magazine published from 1939 to 1953. The editor was Mary Gnaedinger. It was launched by the Munsey Company as a way to reprint the many science fiction and fantasy stories which had appeared over the preceding decades in Munsey magazines such as Argosy. From its first issue, dated September/October 1939, Famous Fantastic Mysteries was an immediate success. Less than a year later, a companion magazine, Fantastic Novels, was launched.

Frequently reprinted authors included George Allan England, A. Merritt, and Austin Hall; the artwork was also a major reason for the success of the magazine, with artists such as Virgil Finlay and Lawrence Stevens contributing some of their best work. In late 1942, Popular Publications acquired the title from Munsey, and Famous Fantastic Mysteries stopped reprinting short stories from the earlier magazines. It continued to reprint longer works, including titles by G. K. Chesterton, H. G. Wells, and H. Rider Haggard. Original short fiction also began to appear, including Arthur C. Clarke's "Guardian Angel", which would later form the first section of his novel Childhood's End. In 1951, the publishers experimented briefly with a large digest format, but returned quickly to the original pulp layout. The magazine ceased publication in 1953, almost at the end of the pulp era.

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